Science Says!
N-163
Welcome to Issue 163 of Science Says! Our weekly newsletter where you’ll learn the latest healthy aging and C15:0 research news that our team of doctors, scientists, and experts are most excited about—without having to go search for it.
Eric and Steph
Co-Founders, Doctors, Nerds
What Dr. Stephanie Venn-Watson, our co-founder and author of The Longevity Nutrient and over 80 peer-reviewed scientific publications, is reading.
The updated Dietary Guidelines for Americans (2026-2030) turned the food pyramid upside down. At the top? Whole fat dairy products, including cheese and whole fat milk, at the top. The reasoning? Whole fat dairy products can offer a suite of beneficial nutrients, including C15:0, that support our long-term health. Alas, these products also have high levels of some fats that are known to be proinflammatory.
A new peer-reviewed study was just published which evaluated fatty acid levels not only in whole fat cow’s milk, but milks from other ruminants. They also measured C15:0 in human milk and infant formulas. This week, let’s dive into how different milk sources stack up as they relate to C15:0… and how those levels have been changing over time.
So, which milks have the highest C15:0 levels?
Najjar et al. showed that, among ruminants, cow’s milk ruled the herd. Here’s a breakdown of the amount of C15:0 (based on the % among all fatty acids) measured in different whole fat milks:
If you’re wondering about plant-based milks, so did Moore et al. This is what they found regarding C15:0 levels:
So… whole fat cow’s milk is the best source of dietary C15:0, while plant-based milks basically don’t have C15:0. And if you happen to be drinking camel or buffalo milk, they come in a distant second place.
This is important because, as we have extensively shared, 100+ peer-reviewed studies support the long-term health benefits of C15:0 (check out all the studies at DiscoverC15.com/resources). And understanding where we can (and can’t) get our dietary C15:0 matters.
Our first dietary source of C15:0: Mom.
As a foundational nutrient, C15:0 should be in the first food we all get: mom-milk. Interestingly Najjar et al. showed, in their study, that there was no detectable C15:0 in human milk. The “interestingly” turns to “disturbingly” when we look at what prior studies have shown that measured C15:0 in mom’s milk.
So, to go from 0.42% of C15:0 in mom-milk during the 1990s to an average of 0.21% between 2018-2023 – and no C15:0 detected in the most recent study, these studies support that declining intake of whole fat dairy products (due in part to movement to plant-based milks) among moms has resulted in lower C15:0 levels in mom’s milk. A summary of data from most of the studies above, is provided below.
We care because higher C15:0 from mom is linked to better development in kiddos.
As we have shared in previous Science Says! issues, multiple studies have linked higher C15:0 from mom’s milk to better health in their children. For example:
Combined, these studies support the need for 1) mom to get adequate C15:0 in her diet, to 2) help her baby get adequate C15:0 in their diet, to 3) enable both mom and baby to enjoy long and healthy lives.
Well, that seems important. What about C15:0 in infant formulas?
Good question! Here’s what a few studies have found:
These studies show that there is high variation of C15:0 levels in infant formulas, with many apparently having little to no C15:0. This is due to the increased use of nonfat and skim fat milk in lieu of whole fat cow’s milk in infant formulas.
Relevance to The Newly-Released Dietary Guidelines for Americans: 2026-2030.
While the new dietary guidelines aren’t perfect, mounting science continues to support the importance of C15:0 to not only our long-term cardiometabolic health as adults, but to our growth and development during our earliest years.
Understanding that:
It is hoped that getting C15:0 back into the lives of moms and children can have a meaningful positive impact on us now and for generations to come.
Have a fantastic week, everyone!
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