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Join the movement to help increase awareness of C15:0 to improve global health.

Resources

Educational materials

For healthcare providers

For healthcare providers

A one-page fact sheet on C15:0 that can be shared with healthcare providers.

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For everyone

For everyone

A one-page fact sheet on C15:0 that can be shared with the general public.

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Highlighted studies

Research Article
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Broader and safer clinically-relevant activities of pentadecanoic acid compared to omega-3: Evaluation of an emerging essential fatty acid…

Stephanie K. Venn-Watson
Camden N. Butterworth
Published: May 26, 2022

A growing body of evidence supports that pentadecanoic acid (C15:0), an odd-chain saturated fat found in butter, is an essential fatty acid that is necessary in the diet to support long-term metabolic and heart health…

Research Article
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Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential?

Stephanie Venn-Watson
Richard Lumpkin
Edward A. Dennis
Published: 18 May 2020

Dietary odd-chain saturated fatty acids (OCFAs) are present in trace levels in dairy fat and some fish and plants. Higher circulating concentrations of OCFAs, pentadecanoic acid (C15:0) and heptadecanoic acid (C17:0)…

Research Article
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Pentadecanoylcarnitine is a newly discovered endocannabinoid with pleiotropic activities relevant to supporting physical and mental health

Stephanie Venn-Watson
John Reiner
Eric D. Jensen
Published: 23 August 2022

As an emerging dietary essential fatty acid, pentadecanoic acid (C15:0) is expected to have bioactive metabolites with broad health benefits.

Research Article
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Effect of an Asian-adapted Mediterranean diet and pentadecanoic acid on fatty liver disease: The TANGO randomized controlled trial

The American Journal of Clinical Nutrition
Published: 29 November 2023

Above and beyond the benefits of a hypo-caloric diet, C15:0 supplementation in this randomized, controlled clinical trial effectively lowered LDL-cholesterol, lowered total fat mass, and caused beneficial shifts in the gut microbiome, including supporting Bifidobacterium adolescentis – a probiotic bacteria that supports longevity.

Research Article
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Pentadecanoic acid (C15:0), an essential fatty acid, shares clinically relevant cell-based activities with leading longevity-enhancing compounds

Stephanie Venn-Watson
Nicholas J. Schork
Published: 30 October 2023

This study, paired the ability of C15:0 to target longevity pathways, hallmarks of aging, and core components of type 2 diabetes, heart disease, cancer, and nonalcoholic fatty liver disease, support C15:0 as an essential nutrient with activities equivalent to, or surpassing, leading longevity-enhancing candidate compounds.

All studies

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A Vital Lifespan Booster: The Essential Role of C15:0

A Vital Lifespan Booster: The Essential Role of C15:0