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Join the movement to help increase awareness of C15:0 to improve global health.

Resources

Educational materials

For healthcare providers

For healthcare providers

A one-page fact sheet on C15:0 that can be shared with healthcare providers.

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For everyone

For everyone

A one-page fact sheet on C15:0 that can be shared with the general public.

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Highlighted studies

Research Article
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Broader and safer clinically-relevant activities of pentadecanoic acid compared to omega-3: Evaluation of an emerging essential fatty acid…

Stephanie K. Venn-Watson
Camden N. Butterworth
Published: May 26, 2022

A growing body of evidence supports that pentadecanoic acid (C15:0), an odd-chain saturated fat found in butter, is an essential fatty acid that is necessary in the diet to support long-term metabolic and heart health…

Research Article
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Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential?

Stephanie Venn-Watson
Richard Lumpkin
Edward A. Dennis
Published: 18 May 2020

Dietary odd-chain saturated fatty acids (OCFAs) are present in trace levels in dairy fat and some fish and plants. Higher circulating concentrations of OCFAs, pentadecanoic acid (C15:0) and heptadecanoic acid (C17:0)…

Research Article
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Pentadecanoylcarnitine is a newly discovered endocannabinoid with pleiotropic activities relevant to supporting physical and mental health

Stephanie Venn-Watson
John Reiner
Eric D. Jensen
Published: 23 August 2022

As an emerging dietary essential fatty acid, pentadecanoic acid (C15:0) is expected to have bioactive metabolites with broad health benefits.

Research Article
AJCN logo

Mild weight loss induced by a Mediterranean-like diet adapted for Asians has multiple beneficial health effects in women with NAFLD. C15:0 supplementation lowers LDL-cholesterol and may cause beneficial shifts in gut microbiome.

The American Journal of Clinical Nutrition
Published: 29 November 2023

Effect of an Asian-adapted Mediterranean diet and pentadecanoic acid on fatty liver disease: The TANGO randomized controlled trial

Research Article
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In summary, our studies and prior literature show that C15:0 and rapamycin, a leading healthspan and longevity-enhancing intervention candidate, share numerous clinically relevant activities, including anti-inflammatory, anticancer, antifibrotic, antimicrobial, and mTOR-inhibiting activities…

Stephanie Venn-Watson
Nicholas J. Schork
Published: 30 October 2023

Pentadecanoic Acid (C15:0), an Essential Fatty Acid, Shares Clinically Relevant Cell-Based Activities with Leading Longevity-Enhancing Compounds

All studies

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A Vital Lifespan Booster: The Essential Role of C15:0

A Vital Lifespan Booster: The Essential Role of C15:0