By naturally targeting receptors throughout out bodies, C15:0 has been shown to:

• Activate the AMPK pathway which maintains cellular homeostasis, regulates glucose metabolism, and is a core component of the human longevity pathway.
• Activate PPAR alpha-delta receptors that regulate metabolism, immunity, mood, appetite, and sleep.
• Inhibit HDAC-6, which reduces cancer cell proliferation.
• Inhibit MAPK and JAK-STAT signaling, which reduces inflammation.

C15:0 reverses multiple drivers of aging and has been shown to:

• Improve cellular resilience against premature breakdown.
• Decrease reactive oxygen species and lipid peroxidation.
• Repair mitochondrial function and increase ATP production.
• Improve cellular signaling.
• Slow a key biomarker of aging rate (i.e. raise hemoglobin).

C15:0 has been shown to lower clinically-relevant biomarkers of chronic disease, including:

• Lower proinflammatory cytokines, including IL-6, MCP-1, VCAM-1, and PAI-1.
• Decrease proliferation of cancer cells.
• Decrease proliferation of fibroblasts to help slow or stop tissue fibrosis.
• Increase glucose uptake by cells.
• Treat multiple human cell disease systems mimicking inflammation, cardiovascular disease, liver cirrhosis, autoimmune disease, and allergies.

Our bodies use C15:0 to make a metabolite called pentadecanoylcarnitine (or PDC), which has been shown to:

• Activate CB1 and CB2 receptors that regulate mood, sleep, inflammation, and pain.
• Activate 5-HT1A and 5-HT1B receptors that help to lower stress.
• Inhibit H1 and H2 histamine receptors, which helps to treat allergy symptoms.